Ecologic Studies Revisited

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Ecologic studies revisited.

Ecologic studies use data aggregated over groups rather than data on individuals. Such studies are popular because they use existing databases and can offer large exposure variation if the data arise from broad geographical areas. Unfortunately, the aggregation of data that define ecologic studies results in an information loss that can lead to ecologic bias. Specifically, ecologic bias arises ...

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Many authors have pointed out that relative-risk estimates derived from ecologic data are vulnerable to biases not found in estimates derived from individual-level data. Nevertheless, biases in ecologic studies still are often dealt with in the same manner as biases in other observational studies, and so are not given adequate treatment. This commentary reviews and illustrates some of the more ...

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BACKGROUND As ecologic studies are often inexpensive to conduct, consideration of the magnitude and direction of ecologic biases may be useful in both study design and sensitivity analysis of results. This paper examines three types of ecologic bias: confounding by group, effect measure modification by group, and non-differential exposure misclassification. METHODS Bias of the risk difference...

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Ecologic studies of rodent reservoirs: their relevance for human health.

Within the past few years, the number of "new" human diseases associated with small-mammal reservoirs has increased dramatically, stimulating renewed interest in reservoir ecology research. A consistent, integrative approach to such research allows direct comparisons between studies, contributes to the efficient use of resources and data, and increases investigator safety. We outline steps dire...

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Methodology Series Module 7: Ecologic Studies and Natural Experiments

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ژورنال

عنوان ژورنال: Annual Review of Public Health

سال: 2008

ISSN: 0163-7525,1545-2093

DOI: 10.1146/annurev.publhealth.29.020907.090821